Case Reports

Neonatal medium-sized vessel vasculitis: A rare case report

M Fallahi, F Abdollahimajd, S Tajalli, R Rakhshan, S Shahnavaz, S Tabatabaee, F Palizban

Abstract


Vasculitis is a rare disorder during the neonatal period. We present a term male neonate of consanguineous parents and birthweight of 4 030 g who presented at 11 days of life with an evolving skin rash. There was no history of drug exposure in the neonate except for routine care. On day 7 of life, multiple erythematous plaques with necrotic or pustular centres appeared. There were no signs of mucosal involvement or sepsis and laboratory findings were normal. Skin biopsy revealed small and intermediate vessel vasculitis. At follow-up 2 weeks after discharge from the hospital, the skin lesions persisted, and at age 2 months, the patient presented with features of severe pneumonia and subsequently died. Vasculitis was reported as the cause of death on postmortem biopsy.

Authors' affiliations

M Fallahi, Neonatal Health Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

F Abdollahimajd, Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Clinical Research Development Unit, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

S Tajalli, Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran

R Rakhshan, Department of Pathology, Shohada-e-Tajrish Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

S Shahnavaz, Neonatal Health Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

S Tabatabaee, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

F Palizban, Neonatal Health Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Cite this article

South African Journal of Child Health 2022;16(2):125.

Article History

Date submitted: 2022-07-22
Date published: 2022-07-22

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